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1

Targeting mitochondrial permeability in cancer drug development

Michael V. Berridge, Patries M. Herst, Alfons Lawen

Journal:

Molecular Nutrition & Food Research

Year:

2009

Language:

english

File:

PDF, 360 KB

english, 2009

2

A highly sensitive colorimetric microplate ferrocyanide assay applied to ascorbate-stimulated transplasma membrane ferricyanide reduction and mitochondrial succinate oxidation

Darius J.R. Lane, Alfons Lawen

Journal:

Analytical Biochemistry

Year:

2008

Language:

english

File:

PDF, 296 KB

english, 2008

3

Mammalian Iron Homeostasis in Health and Disease: Uptake, Storage, Transport, and Molecular Mechanisms of Action

Lawen, Alfons, Lane, Darius J.R.

Journal:

Antioxidants & Redox Signaling

Year:

2013

Language:

english

File:

PDF, 1.51 MB

english, 2013

4

Integration of intracellular signaling: Biological analogues of wires, processors and memories organized by a centrosome 3D reference system

Barvitenko, Nadezhda, Lawen, Alfons, Aslam, Muhammad, Pantaleo, Antonella, Saldanha, Carlota, Skverchinskaya, Elisaveta, Regolini, Marco, Tuszynski, Jack A.

Journal:

Year:

2018

Language:

english

File:

PDF, 2.03 MB

english, 2018

5

Changes in phosphorylation of Ca2+/calmodulin-dependent protein kinase II (CaMKII) in processing of short-term and long-term memories after passive avoidance learning

Weiqin Zhao, Alfons Lawen, Kim T. Ng

Journal:

Journal of Neuroscience Research

Year:

1999

Language:

english

File:

PDF, 308 KB

english, 1999

6

Unspecific activation of caspases during the induction of apoptosis by didemnin B in human cell lines

Karina L. Johnson, David R. Grubb, Alfons Lawen

Journal:

Journal of Cellular Biochemistry

Year:

1999

Language:

english

File:

PDF, 171 KB

english, 1999

7

Apoptosis—an introduction

Journal:

Year:

2003

Language:

english

File:

PDF, 342 KB

english, 2003

8

Book Review: When Cells Die II. A Comprehensive Evaluation of Apoptosis and Programmed Cell Death. Edited by Richard A. Lockshin and Zahra Zakeri.

Journal:

Year:

2004

Language:

english

File:

PDF, 32 KB

english, 2004

9

Characterization of the N-Methyltransferase Activities of the Multifunctional Polypeptide Cyclosporin Synthetase

Tony Velkov, James Horne, Martin J. Scanlon, Ben Capuano, Elizabeth Yuriev, Alfons Lawen

Journal:

Chemistry & Biology

Year:

2011

Language:

english

File:

PDF, 1.53 MB

english, 2011

10

Rapamycin inhibits didemnin B-induced apoptosis in human HL-60 cells: Evidence for the possible involvement of FK506-binding protein 25

Johnson, Karina L, Lawen, Alfons

Journal:

Immunology & Cell Biology

Year:

1999

Language:

english

File:

PDF, 120 KB

english, 1999

11

Effectors of the mammalian plasma membrane NADH-oxidoreductase system. Short-chain ubiquinone analogues as potent stimulators

FranÇois Vaillant, Jari A. Larm, Gabrielle L. McMullen, Ernst J. Wolvetang, Alfons Lawen

Journal:

Journal of Bioenergetics and Biomembranes

Year:

1996

Language:

english

File:

PDF, 857 KB

english, 1996

12

Another piece of the puzzle of apoptotic cytochrome c release

Journal:

Molecular Microbiology

Year:

2007

Language:

english

File:

PDF, 100 KB

english, 2007

13

Inhibition of Aβ aggregation and neurotoxicity by the 39-kDa receptor-associated protein

Megan L. Kerr, Robert Gasperini, Marie E. Gibbs, Xu Hou, Claire E. Shepherd, Dudley K. Strickland, Lisa Foa, Alfons Lawen, David H. Small

Journal:

Journal of Neurochemistry

Year:

2010

Language:

english

File:

PDF, 624 KB

english, 2010

14

Neurones express glutamine synthetase when deprived of glutamine or interaction with astrocytes

Samantha P. Fernandes, Ralf Dringen, Alfons Lawen, Stephen R. Robinson

Journal:

Journal of Neurochemistry

Year:

2010

Language:

english

File:

PDF, 495 KB

english, 2010

15

Bioethics needs a distinct voice if it is to aid science

Journal:

Year:

2003

Language:

english

File:

PDF, 56 KB

english, 2003

16

Mitochondrial cytochrome c release is caspase-dependent and does not involve mitochondrial permeability transition in didemnin B-induced apoptosis

Grubb, David R, Ly, Jennifer D, Vaillant, François, Johnson, Karina L, Lawen, Alfons

Journal:

Year:

2001

Language:

english

File:

PDF, 314 KB

english, 2001

17

Photoaffinity Labeling of the N-methyltransferase Domains of Cyclosporin Synthetase

Tony Velkov, Alfons Lawen

Journal:

Photochemistry and Photobiology

Year:

2003

Language:

english

File:

PDF, 1.33 MB

english, 2003

18

Plasma membrane NADH-oxidoreductase in cells carrying mitochondrial DNA G11778A mutation and in cells devoid of mitochondrial DNA (ρ0)

Safarina G. Malik, François Vaillant, Alfons Lawen

Journal:

Year:

2004

Language:

english

File:

PDF, 217 KB

english, 2004

19

Transplasma membrane electron transport comes in two flavors

Darius J. R. Lane, Alfons Lawen

Journal:

Year:

2008

Language:

english

File:

PDF, 1.04 MB

english, 2008

20

Characterization of VDAC1 as a plasma membrane NADH-oxidoreductase

Mark A. Baker, Jennifer D. Ly, Alfons Lawen

Journal:

Year:

2004

Language:

english

File:

PDF, 65 KB

english, 2004

21

Cyclosporin A, an inhibitor of calcineurin, impairs memory formation in day-old chicks

Pauleen C. Bennett, Zhao Weiqin, Alfons Lawen, Kim T. Ng

Journal:

Year:

1996

Language:

english

File:

PDF, 1.04 MB

english, 1996

22

Voltage-dependent anion-selective channel (VDAC) in the plasma membrane

Vito De Pinto, Angela Messina, Darius J.R. Lane, Alfons Lawen

Journal:

Year:

2010

Language:

english

File:

PDF, 418 KB

english, 2010

23

Ascorbate and plasma membrane electron transport—Enzymes vs efflux

Darius J.R. Lane, Alfons Lawen

Journal:

Free Radical Biology and Medicine

Year:

2009

Language:

english

File:

PDF, 803 KB

english, 2009

24

Cyclosporin A, FK506 and rapamycin produce multiple, temporally distinct, effects on memory following single-trial, passive avoidance training in the chick

Pauleen C Bennett, Lisa Schmidt, Alfons Lawen, Penny Moutsoulas, Kim T Ng

Journal:

Year:

2002

Language:

english

File:

PDF, 215 KB

english, 2002

25

Novel effects on memory observed following unilateral intracranial administration of okadaic acid, cyclosporin A, FK506 and [MeVal4]CyA

Pauleen C. Bennett, Penny Moutsoulas, Alfons Lawen, Eloise Perini, Kim T. Ng

Journal:

Year:

2003

Language:

english

File:

PDF, 251 KB

english, 2003

26

Mitogen-responsive S6 kinase

Alfons LAWEN, Matthias BURGER, Oskar H. W. MARTINI

Journal:

Year:

1989

Language:

english

File:

PDF, 1.29 MB

english, 1989

27

Insulin-induced S6 kinase activation in HeLa cells and its reversal by hyperthermic stress

Matthias BURGER, Alfons LAWEN, Oskar H. W. MARTINI

Journal:

Year:

1989

Language:

english

File:

PDF, 942 KB

english, 1989

28

A chick embryo fibroblast protein kinase recognizing ribosomal protein S6: Activity increase after serum stimulation

Alfons Lawen, Oskar H.W. Martini

Journal:

Year:

1985

Language:

english

File:

PDF, 446 KB

english, 1985

29

Cyclosporin synthetase is a 1.4 MDa multienzyme polypeptide Re-evaluation of the molecular mass of various peptide synthetases

Bettina Schmidt, Detlev Riesner, Alfons Lawen, Horst Kleinkauf

Journal:

Year:

1992

Language:

english

File:

PDF, 654 KB

english, 1992

30

Reversible denaturation of cyclosporin synthetase by urea

Joachim Dittmann, François Vaillant, Horst Kleinkauf, Alfons Lawen

Journal:

Year:

1996

Language:

english

File:

PDF, 412 KB

english, 1996

31

Protein tyrosine kinase inhibitors prevent didemnin B-induced apoptosis in HL-60 cells

Karina L. Johnson, François Vaillant, Lawen Alfons

Journal:

Year:

1996

Language:

english

File:

PDF, 351 KB

english, 1996

32

Voltage-dependent anion-selective channel 1 (VDAC1)—a mitochondrial protein, rediscovered as a novel enzyme in the plasma membrane

Alfons Lawen, Jennifer D. Ly, Darius J.R. Lane, Kristof Zarschler, Angela Messina, Vito De Pinto

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2005

Language:

english

File:

PDF, 220 KB

english, 2005

33

An improved purification procedure for cyclosporin synthetase

Tony Velkov, Lloyd George Singaretnam, Alfons Lawen

Journal:

Protein Expression and Purification

Year:

2006

Language:

english

File:

PDF, 727 KB

english, 2006

34

Peptidyl-prolyl-cis/trans-isomerase activity may be necessary for memory formation

Pauleen C Bennett, Lloyd G Singaretnam, Wei-Qin Zhao, Alfons Lawen, Kim T Ng

Journal:

Year:

1998

Language:

english

File:

PDF, 135 KB

english, 1998

35

The Glutamate Aspartate Transporter (GLAST) Mediatesl-Glutamate-Stimulated Ascorbate-Release Via Swelling-Activated Anion Channels in Cultured Neonatal Rodent Astrocytes

Lane, Darius J. R., Lawen, Alfons

Journal:

Cell Biochemistry and Biophysics

Year:

2013

Language:

english

File:

PDF, 403 KB

english, 2013

36

Two routes of iron accumulation in astrocytes: ascorbate-dependent ferrous iron uptake via the divalent metal transporter (DMT1) plus an independent route for ferric iron

Lane, Darius J.R., Robinson, Stephen R., Czerwinska, Hania, Bishop, Glenda M., Lawen, Alfons

Journal:

Biochemical Journal

Year:

2010

Language:

english

File:

PDF, 581 KB

english, 2010

37

Plasma Membrane NADH-Oxidoreductase System: A Critical Review of the Structural and Functional Data

Baker, Mark A., Lawen, Alfons

Journal:

Antioxidants & Redox Signaling

Year:

2000

Language:

english

File:

PDF, 1.33 MB

english, 2000

38

Involvement of Reactive Oxygen Species in Capsaicinoid-induced Apoptosis in Transformed Cells

Macho, Antonio, Sancho, Rocío, Minassi, Alberto, Appendino, Giovanni, Lawen, Alfons, Muñoz, Eduardo

Journal:

Free Radical Research

Year:

2003

Language:

english

File:

PDF, 299 KB

english, 2003

39

Biosynthesis of cyclosporins and other natural peptidyl prolyl cis/trans isomerase inhibitors

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

2014

File:

PDF, 659 KB

2014

40

Prediction of signaling cross-talks contributing to acquired drug resistance in breast cancer cells by Bayesian statistical modeling

Azad, AKM, Lawen, Alfons, Keith, Jonathan M

Journal:

BMC Systems Biology

Year:

2015

Language:

english

File:

PDF, 2.29 MB

english, 2015

41

Isolation and Partial Characterization of Cyclosporin Synthetase from a Cyclosporin Non-Producing Mutant of Beauveria nivea

DITTMANN, Joachim, LAWEN, Alfons, ZOCHER, Rainer, KLEINKAUF, Horst

Journal:

Biological Chemistry Hoppe-Seyler

Year:

1990

Language:

english

File:

PDF, 916 KB

english, 1990

42

Transplasma membrane electron transport: enzymes involved and biological function

Ly, Jennifer D., Lawen, Alfons

Journal:

Year:

2003

Language:

english

File:

PDF, 424 KB

english, 2003

43

A role for Na + /H + exchangers and intracellular pH in regulating vitamin C-driven electron transport across the plasma membrane

Lane, Darius J.R., Robinson, Stephen R., Czerwinska, Hania, Lawen, Alfons

Journal:

Biochemical Journal

Year:

2010

Language:

english

File:

PDF, 398 KB

english, 2010

44

Cell-free biosynthesis of new cyclosporins.

LAWEN, ALFONS, TRADER, RENÉ, GEYL, DIETER, ZOCHER, RAINER, KLEINKAUF, HORST

Journal:

The Journal of Antibiotics

Year:

1989

Language:

english

File:

PDF, 480 KB

english, 1989

45

[Progress in Medicinal Chemistry] Volume 33 || 2 Biosynthesis and Mechanism of Action of Cyclosporins

Year:

1996

Language:

english

File:

PDF, 2.14 MB

english, 1996

46

A Rapid and Specific Microplate Assay for the Determination of Intra- and Extracellular Ascorbate in Cultured Cells

Lane, Darius J. R., Lawen, Alfons

Journal:

Journal of Visualized Experiments

Year:

2014

Language:

english

File:

PDF, 337 KB

english, 2014

47

Bayesian model of signal rewiring reveals mechanisms of gene dysregulation in acquired drug resistance in breast cancer

Azad, A. K. M., Lawen, Alfons, Keith, Jonathan M., Ahmad, Aamir

Journal:

Year:

2017

Language:

english

File:

PDF, 3.04 MB

english, 2017

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